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Potential Utility of Ultrasound-Enhanced Delivery of Antibiotics, Anti-Inflammatory Agents, and Nutraceuticals: A Mini Review
Antibiotics ( IF 4.8 ) Pub Date : 2022-09-22 , DOI: 10.3390/antibiotics11101290
J Karim Ead 1 , Arjun Sharma 2 , Miranda Goransson 3 , David G Armstrong 1
Affiliation  

Ultrasound technology has therapeutic properties that can be harnessed to enhance topical drug delivery in a process known as phonophoresis. The literature on this method of drug delivery is currently sparse and scattered. In this review, we explore in vivo and in vitro controlled trials as well as studies detailing the mechanism of action in phonophoresis to gain a clearer picture of the treatment modality and explore its utility in chronic wound management. Upon review, we believe that phonophoresis has the potential to aid in chronic wound management, particularly against complicated bacterial biofilms. This would offer a minimally invasive wound management option for patients in the community.

中文翻译:

超声增强抗生素、抗炎药和保健品递送的潜在效用:小型回顾

超声技术具有治疗特性,可用于在称为透声疗法的过程中增强局部药物输送。目前关于这种药物输送方法的文献很少且分散。在这篇综述中,我们探索了体内和体外对照试验以及详细说明透声疗法作用机制的研究,以更清楚地了解治疗方式并探索其在慢性伤口管理中的效用。经过审查,我们认为超声导入有可能有助于慢性伤口管理,特别是针对复杂的细菌生物膜。这将为社区患者提供微创伤口管理选择。
更新日期:2022-09-22
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