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Intensification of catechin extraction from the bark of Syzygium cumini using ultrasonication: Optimization, characterization, degradation analysis and kinetic studies
Chemical Engineering and Processing: Process Intensification ( IF 4.3 ) Pub Date : 2022-09-22 , DOI: 10.1016/j.cep.2022.109147
Yogesh A. Bhadange , Virendra Kumar Saharan , Shirish H Sonawane , Grzegorz Boczkaj

Catechin is a prominent polyphenolic component that possesses various medicinal properties. Present work communicates the intensification and optimization of catechin extraction from the bark of Syzygium cumini tree using stirred reactor, soxhlet, ultrasonic bath, and ultrasonic horn technique. The optimization of several parameters such as type of solvent, solid to solvent ratio (1:100 w/v), speed of agitation (300 RPM), extraction temperature (40 °C), and amplitude (20%) has been done for the maximization of catechin extraction yield. The kinetic (second-order rate mechanism) and degradation analysis (based on LC-MS characterization) have been performed to understand the extraction mechanism, forecast extraction stability, and avoid unwanted catechin degradation during ultrasonication. The effectiveness of different extraction techniques was compared based on the yield of catechin per unit of power dissipated. These studies revealed that ultrasonic horn produced maximum extraction yield (13.8 mg/g) in a shorter time (5 min), consumed less energy (0.2974 kJ), and gave the highest extraction rate (0.0910 g/mg.min) as compared to other techniques. The effectiveness of extraction using the ultrasonic horn was 39.67 mg/g.kJ. A mathematical model using the linear regression method was investigated for the process, which shows numerical correlation and significance factor between the yield and all other parameters.



中文翻译:

利用超声波强化从蒲桃树皮中提取儿茶素:优化、表征、降解分析和动力学研究

儿茶素是一种突出的多酚成分,具有多种药用特性。目前的工作交流了从蒲公英树皮中提取儿茶素的强化和优化树使用搅拌反应器、索氏、超声波浴和超声波喇叭技术。对溶剂类型、固溶比 (1:100 w/v)、搅拌速度 (300 RPM)、萃取温度 (40 °C) 和振幅 (20%) 等参数进行了优化儿茶素提取率的最大化。已经进行了动力学(二级速率机制)和降解分析(基于 LC-MS 表征)以了解提取机制、预测提取稳定性并避免超声处理过程中不必要的儿茶素降解。基于每单位功率耗散的儿茶素产量比较不同提取技术的有效性。这些研究表明,超声波喇叭在更短的时间(5 分钟)内产生最大的提取率(13.8 mg/g),消耗更少的能量(0. 2974 kJ),与其他技术相比,提取率最高 (0.0910 g/mg.min)。使用超声波喇叭提取的有效性为 39.67 mg/g.kJ。对该过程使用线性回归方法的数学模型进行了研究,该模型显示了产量与所有其他参数之间的数值相关性和显着性因子。

更新日期:2022-09-22
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