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Diagnostic and prognostic performance of urinary neutrophil gelatinase-associated lipocalin in patients with cirrhosis and acute kidney injury
Hepatology ( IF 13.5 ) Pub Date : 2022-09-20 , DOI: 10.1002/hep.32799 Carmine Gambino 1 , Salvatore Piano 1 , Matteo Stenico 1 , Marta Tonon 1 , Alessandra Brocca 1 , Valeria Calvino 1 , Simone Incicco 1 , Nicola Zeni 1 , Roberta Gagliardi 1 , Chiara Cosma 2 , Martina Zaninotto 2 , Patrizia Burra 3 , Umberto Cillo 4 , Daniela Basso 2 , Paolo Angeli 1
Hepatology ( IF 13.5 ) Pub Date : 2022-09-20 , DOI: 10.1002/hep.32799 Carmine Gambino 1 , Salvatore Piano 1 , Matteo Stenico 1 , Marta Tonon 1 , Alessandra Brocca 1 , Valeria Calvino 1 , Simone Incicco 1 , Nicola Zeni 1 , Roberta Gagliardi 1 , Chiara Cosma 2 , Martina Zaninotto 2 , Patrizia Burra 3 , Umberto Cillo 4 , Daniela Basso 2 , Paolo Angeli 1
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Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI. The aim of this study was to investigate the use of uNGAL in (1) the differential diagnosis of AKI, (2) predicting the response to terlipressin and albumin in patients with hepatorenal syndrome-AKI (HRS-AKI), and (3) predicting in-hospital mortality in patients with AKI.
中文翻译：
肝硬化和急性肾损伤患者尿中性粒细胞明胶酶相关脂质运载蛋白的诊断和预后表现
急性肾损伤 (AKI) 通常发生在失代偿性肝硬化患者中。尿液中性粒细胞明胶酶相关脂质运载蛋白 (uNGAL) 有助于区分 AKI 的不同病因。本研究的目的是研究 uNGAL 在 (1) AKI 的鉴别诊断，(2) 预测肝肾综合征 AKI (HRS-AKI) 患者对特利加压素和白蛋白的反应，以及 (3) 预测AKI 患者的院内死亡率。
更新日期：2022-09-20
中文翻译：
肝硬化和急性肾损伤患者尿中性粒细胞明胶酶相关脂质运载蛋白的诊断和预后表现
急性肾损伤 (AKI) 通常发生在失代偿性肝硬化患者中。尿液中性粒细胞明胶酶相关脂质运载蛋白 (uNGAL) 有助于区分 AKI 的不同病因。本研究的目的是研究 uNGAL 在 (1) AKI 的鉴别诊断，(2) 预测肝肾综合征 AKI (HRS-AKI) 患者对特利加压素和白蛋白的反应，以及 (3) 预测AKI 患者的院内死亡率。
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