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Sural Sparing Pattern and Sensory Ratio as Electrodiagnostic and Prognostic Markers in Pediatric Guillain–Barré Syndrome
Neuropediatrics ( IF 1.4 ) Pub Date : 2022-12-27 , DOI: 10.1055/a-1941-4513
Çağatay Günay 1 , Gamze Sarıkaya Uzan 1 , Semra Hız Kurul 1 , Uluç Yiş 1
Affiliation  

Background We aimed to evaluate the presence of sural sparing pattern (SSP) and sensory ratio in pediatric Guillain–Barré syndrome (GBS), their distribution to subtypes, and their relationship with demographic and clinical features with a focus on the disability and muscle strength. Methods This single-center retrospective study was conducted on pediatric GBS patients of both sexes with 2 years follow-up and two nerve conduction studies in which SSP and sensory ratio were calculated. Three subgroups of SSP were formed by separate calculation of median (SSP-m) and ulnar (SSP-u) and both median and ulnar sensory nerve action potentials (SNAPs; SSP-total). Muscle strength and disability were evaluated with the Medical Research Council (MRC) sum score and Hughes functional grading scale (HFGS), respectively. Results SSP total was identified in 70.6% (n: 24) of the patients, while sensory ratio >1 was observed in 20 (66.7%) patients. Patients with SSP-m, SSP-u, SSP-total, or sensory ratio >1 had higher HFGS scores, while patients with SSP-m, SSP-u, or SSP-total had lower MRC sum scores. SSP parameters were significantly associated with muscle strength and disability scores in acute motor axonal neuropathy patients. Conclusion Both SSP and sensory ratio can be used for diagnostic and prognostic purposes. Disability and muscle strength are associated with SSP and sensory ratio in pediatric GBS.

中文翻译:

腓肠肌保留模式和感觉比率作为小儿格林-巴利综合征的电诊断和预后标志物

背景 我们的目的是评估小儿格林-巴利综合征 (GBS) 中腓肠保留模式 (SSP) 和感觉比率的存在、它们在亚型中的分布,以及它们与人口统计学和临床​​特征的关系,重点是残疾和肌肉力量。方法 这项单中心回顾性研究是对两性的儿科 GBS 患者进行的,随访 2 年,并进行了两项神经传导研究,其中计算了 SSP 和感觉比率。通过分别计算中位 (SSP-m) 和尺侧 (SSP-u) 以及中位和尺侧感觉神经动作电位 (SNAPs;SSP-total),形成 SSP 的三个亚组。肌肉力量和残疾分别用医学研究委员会 (MRC) 总分和休斯功能分级量表 (HFGS) 进行评估。结果 在 70 个中确定了 SSP 总数。6% (n: 24) 的患者,而在 20 名 (66.7%) 患者中观察到感觉比率 > 1。SSP-m、SSP-u、SSP-total 或感觉比 >1 的患者具有较高的 HFGS 评分,而 SSP-m、SSP-u 或 SSP-total 的患者具有较低的 MRC 总分。SSP 参数与急性运动轴索性神经病患者的肌肉力量和残疾评分显着相关。结论 SSP 和感觉比率均可用于诊断和预后目的。残疾和肌肉力量与儿科 GBS 中的 SSP 和感觉比率相关。SSP 参数与急性运动轴索性神经病患者的肌肉力量和残疾评分显着相关。结论 SSP 和感觉比率均可用于诊断和预后目的。残疾和肌肉力量与儿科 GBS 中的 SSP 和感觉比率相关。SSP 参数与急性运动轴索性神经病患者的肌肉力量和残疾评分显着相关。结论 SSP 和感觉比率均可用于诊断和预后目的。残疾和肌肉力量与儿科 GBS 中的 SSP 和感觉比率相关。
更新日期:2022-12-28
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