The interaction of CD300lf and ceramide reduces the development of periodontitis by inhibiting osteoclast differentiation,Journal of Clinical Periodontology

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The interaction of CD300lf and ceramide reduces the development of periodontitis by inhibiting osteoclast differentiation
Journal of Clinical Periodontology ( IF 6.7 ) Pub Date : 2022-09-12 , DOI: 10.1111/jcpe.13724
Qiannan Hu ₁ , Lisa Yang ₁ , Zhongyan Shan ₁ , Shuqiong Wen ₁ , Huanzi Lu ₁ , Zhaolei Zou ₁ , Junyi Guo ₁ , Xiangqi Liu ₁ , Wenqiang Xie ₁ , Yang Cao ₁ , Zhi Wang ₁ , Le Yang ₁ , Xi Wang ₁

Affiliation

The regulation of osteoclasts (OCs) by inhibitory immunoreceptors maintains bone homeostasis and is considered an important determinant of the extent of periodontal pathology. The aim of this study was to investigate the role of the inhibitory immunoreceptor CD300lf and its ligand ceramide in osteoclastogenesis in periodontitis.

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