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The Added Value of Pharmacotherapy to Cognitive Behavior Therapy And Vice Versa in the Treatment of Alcohol Use Disorders: A Systematic Review.
Alcohol and Alcoholism ( IF 2.8 ) Pub Date : 2022-11-11 , DOI: 10.1093/alcalc/agac043
Jan van Amsterdam 1 , Peter Blanken 2 , Renske Spijkerman 2 , Wim van den Brink 1 , Vincent Hendriks 2, 3
Affiliation  

AIM To explore whether combined interventions i.e. psychotherapeutic plus psychosocial interventions are more effective than monotherapies in the treatment of alcohol use disorders. METHODS Systematic review of the results of randomized controlled trials that compared combined therapies with monotherapies (either pharmacotherapy or psychotherapy). RESULTS The search resulted in 28 eligible studies. Data from these RCTs showed that 10 out of 19 RCTs (53%) demonstrated an added value of combined therapy (psychotherapy + pharmacotherapy) compared to psychotherapy only, whereas only three out of nine RCTs (33%) comparing combined therapy with pharmacotherapy showed a possible added value for combined therapy. CONCLUSIONS Pharmacotherapy is effective to treat AUD with or without psychotherapy and that psychotherapy can best be offered in combination with pharmacotherapy.

中文翻译:

药物疗法对认知行为疗法的附加值,反之亦然在酒精使用障碍的治疗中:系统评价。

目的 探讨联合干预即心理治疗加社会心理干预在治疗酒精使用障碍方面是否比单一疗法更有效。方法 系统评价将联合疗法与单一疗法(药物疗法或心理疗法)进行比较的随机对照试验的结果。结果 检索结果为 28 项符合条件的研究。来自这些随机对照试验的数据显示,19 项随机对照试验中有 10 项 (53%) 证明联合治疗(心理治疗 + 药物治疗)与仅心理治疗相比具有附加值,而九项随机对照试验中只有三项 (33%) 将联合治疗与药物治疗进行比较显示联合治疗的可能附加值。
更新日期:2022-09-09
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