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Cytologic features of metastatic epithelioid uterine leiomyosarcoma to the pancreas
Diagnostic Cytopathology ( IF 1.3 ) Pub Date : 2022-09-09 , DOI: 10.1002/dc.25051
Naomi L Hardy 1 , Andrew Canakis 2 , Paul N Staats 3 , Peter Darwin 2 , Teklu Legesse 3
Affiliation  

Although uterine leiomyosarcoma (ULMS) is a rare disease, it accounts for a significant proportion uterine cancer-related deaths due to frequent metastasis and chemoresistance. The WHO currently recognizes the conventional (spindle), myxoid, and epithelioid variants of ULMS, the latter of which is the rarest, least understood, and cited as clinically more aggressive than the other variants. Descriptions of the histologic features of epithelioid ULMS are extremely limited, and are absent from the cytology literature which has only published descriptions of conventional ULMS or epithelioid variants of other LMS primaries. Therefore, we present a unique case of metastatic epithelioid ULMS to an unusual location, the pancreas, along with its cytologic features on endoscopic ultrasound-guided fine needle aspiration not previously described including pseudoglandular arrangements, scant cytoplasm, and frequent molding.

中文翻译:

胰腺转移性上皮样子宫平滑肌肉瘤的细胞学特征

尽管子宫平滑肌肉瘤 (ULMS) 是一种罕见疾病,但由于频繁转移和化疗耐药,它在子宫癌相关死亡中占很大比例。WHO 目前承认 ULMS 的常规(纺锤体)、粘液样和上皮样变体,后者最罕见、了解最少,并且被认为在临床上比其他变体更具侵袭性。上皮样 ULMS 的组织学特征的描述非常有限,并且在细胞学文献中没有,这些文献只发表了对常规 ULMS 或其他 LMS 原发性上皮样变体的描述。因此,我们提出了一个转移性上皮样 ULMS 的独特病例,该病例转移到一个不寻常的位置,即胰腺,
更新日期:2022-09-09
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