Impact of body composition and genotype on haemodynamics during surgery for pheochromocytoma and paraganglioma,Journal of Cachexia, Sarcopenia and Muscle

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Impact of body composition and genotype on haemodynamics during surgery for pheochromocytoma and paraganglioma
Journal of Cachexia, Sarcopenia and Muscle ( IF 8.9 ) Pub Date : 2022-09-06 , DOI: 10.1002/jcsm.13071
Yingxian Pang _{1,

2} , Minghao Li _{1,

3} , Jingjing Jiang ₄ , Xiang Chen ₁ , Yan Fu ₅ , Cikui Wang ₆ , Yao He ₁ , Yuanzhe Zhao ₅ , Yong Wang ₁ , Xiao Guan ₁ , Liang Zhang ₁ , Xiaowen Xu ₁ , Yu Gan ₁ , Yalin Liu ₇ , Yaoling Xie ₅ , Tingyuan Tang ₅ , Jing Wang ₈ , Bin Xie ₈ , Zhihao Liang ₁ , Danlei Chen ₁ , Haipeng Liu ₅ , Changyong Chen ₅ , Graeme Eisenhofer _{3,

9} , Longfei Liu _{1,

2} , Xiaoping Yi _{2,

5,

10,

11,

12} , Bihong T Chen ₁₃

Affiliation

Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.
National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.
Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, P. R. China.
Department of Radiology, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.
Department of Urology, Hubei Armed Police Corps Hospital, Wuchang, P. R. China.
Xiangya School of Medicine, Central South University, Changsha, Hunan, P. R. China.
Department of Pathology, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.
Institute of Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, Dresden, Germany.
Hunan Key Laboratory of Skin Cancer and Psoriasis, Changsha, Hunan, P. R. China.
Hunan Engineering Research Center of Skin Health and Disease, Changsha, Hunan, P. R. China.
National Engineering Research Center of Personalized Diagnostic and Therapeutic Technology, Central South University, Changsha, Hunan, P. R. China.
Department of Diagnostic Radiology, City of Hope National Medical Center, Duarte, CA, USA.

Maintaining intraoperative haemodynamic stability can reduce cardiovascular complications during surgery for pheochromocytoma and paraganglioma (PPGL). Risk factors such as tumour size and catecholamine levels are reported to predict haemodynamic responses during surgery for PPGL. We hypothesized that additional factors including body composition and genetic information could further improve prediction.

中文翻译：

身体成分和基因型对嗜铬细胞瘤和副神经节瘤手术中血流动力学的影响

维持术中血流动力学稳定可以减少嗜铬细胞瘤和副神经节瘤 (PPGL) 手术期间的心血管并发症。据报道，肿瘤大小和儿茶酚胺水平等风险因素可预测 PPGL 手术期间的血液动力学反应。我们假设包括身体成分和遗传信息在内的其他因素可以进一步改善预测。

更新日期：2022-09-06

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