Background. Morbid obesity is one of the fastest-growing subgroups of obesity and is associated with high mortality, with an estimated 2.8 million people dying from obesity each year. Objective. This research sets out to elucidate the impact of sevoflurane (Sevo) inhalation anesthesia on the clinical outcome of morbidly obese (MO) patients undergoing laparoscopic bariatric surgery (LBS). Methods. A retrospective study was conducted on 150 MO patients undergoing LBS in the Second Affiliated Hospital of Xi’an Jiaotong University from November 2019 to November 2021. According to the difference of anesthesia methods, 100 patients with Sevo anesthesia were set as group A, and 50 patients with propofol (P) anesthesia were set as group B. Intergroup comparisons were performed in terms of eye-opening time, tracheal intubation removal time, directional force recovery, heart rate (HR), mean arterial pressure (MAP), peak airway pressure (P_peak), plateau pressure (P_plat), standard time out of PACU, postoperative food intake (FI), length of stay (LOS), and complication rate. Results. Group A had a shorter time to open eyes, remove tracheal intubation, and restore directional force than Group B, with better recovery of HR, MAP, P_peak, and P_plat. Group A was also superior to Group B in the standard time out of PACU, postoperative FI, and LOS, with a lower complication rate. Conclusions. Sevo inhalation anesthesia is more effective and safer for MO patients undergoing LBS.

中文翻译：

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七氟醚吸入麻醉对接受腹腔镜减肥手术的病态肥胖患者临床结局的影响

背景。病态肥胖是肥胖增长最快的亚组之一，与高死亡率相关，估计每年有 280 万人死于肥胖。客观。本研究旨在阐明七氟醚 (Sevo) 吸入麻醉对接受腹腔镜减肥手术 (LBS) 的病态肥胖 (MO) 患者临床结果的影响。方法. 回顾性研究2019年11月至2021年11月在西安交通大学第二附属医院接受LBS的150例MO患者，根据麻醉方式的不同，将100例Sevo麻醉患者作为A组，50例患者作为A组。以丙泊酚（P）麻醉患者为B组，比较睁眼时间、气管插管拔除时间、定向力恢复、心率（HR）、平均动脉压（MAP）、气道峰压(P _peak )、平台压 (P _plat )、PACU 标准退出时间、术后食物摄入量 (FI)、住院时间 (LOS) 和并发症发生率。结果. A组睁眼、拔除气管插管、恢复定向力的时间较B组短，HR、MAP、P _peak、P _plat恢复较好。A组在PACU标准退出时间、术后FI和LOS方面也优于B组，并发症发生率较低。结论。Sevo 吸入麻醉对接受 LBS 的 MO 患者更有效、更安全。