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Cathelicidin-related antimicrobial peptide mediates skeletal muscle degeneration caused by injury and Duchenne muscular dystrophy in mice
Journal of Cachexia, Sarcopenia and Muscle ( IF 8.9 ) Pub Date : 2022-09-04 , DOI: 10.1002/jcsm.13065
Moon-Chang Choi 1 , Jiwon Jo 1 , Myeongjin Lee 1 , Jonggwan Park 2 , Tso-Pang Yao 3 , Yoonkyung Park 1
Affiliation  

Cathelicidin, an antimicrobial peptide, plays a key role in regulating bacterial killing and innate immunity; however, its role in skeletal muscle function is unknown. We investigated the potential role of cathelicidin in skeletal muscle pathology resulting from acute injury and Duchenne muscular dystrophy (DMD) in mice.

中文翻译:

Cathelicidin 相关抗菌肽介导小鼠损伤引起的骨骼肌退化和 Duchenne 肌营养不良症

Cathelicidin 是一种抗菌肽,在调节细菌杀灭和先天免疫方面起着关键作用;然而,它在骨骼肌功能中的作用尚不清楚。我们研究了导管素在小鼠急性损伤和杜氏肌营养不良症 (DMD) 引起的骨骼肌病理学中的潜在作用。
更新日期:2022-09-04
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