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Progression of vascular function and blood pressure in a mouse model of Kawasaki disease
bioRxiv - Pharmacology and Toxicology Pub Date : 2022-08-26 , DOI: 10.1101/2022.08.25.505303
Mia DelVechio , Juliano V Alves , Alina Z Saiyi , Shubhnita Singh , Joseph Galley , Wanessa M. C. Awata , Ariane Bruder-Nascimento , Thiago Bruder-Nascimento

Background Kawasaki disease (KD) is a systemic vasculitis of childhood characterized by vascular damage in the acute stage, which can persist into the late stage. Aneurysms, myocardial infarction, and death are long-standing complications associated with KD. The vascular mechanisms in the cardiovascular risk of KD are not fully studied. Herein, we investigated the vascular function and blood pressure regulation in a murine model of KD.

中文翻译:

川崎病小鼠模型中血管功能和血压的进展

背景川崎病(KD)是一种儿童系统性血管炎,其特点是急性期血管损伤,可持续至晚期。动脉瘤、心肌梗死和死亡是与 KD 相关的长期并发症。KD心血管风险的血管机制尚未得到充分研究。在此,我们研究了 KD 小鼠模型中的血管功能和血压调节。
更新日期:2022-08-29
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