The scale-up synthesis of covalent organic frameworks (COFs) with uniform structure and properties is of great importance for their practical applications. Here, we proposed a facile way to massively produce phthalocyanine-like COFs (COF_BTC) via high-gravity intensified synthesis. Alcoholic solvent and basic catalyst were discovered synergically improved the formation of COF_BTC. High concentration and reaction temperature were beneficial for high production as well. The intensified mass and heat transfer at high-gravity promoted the scaling-up of COF_BTC with homogeneous structures and properties. A high space time yield of 305.9 kg∙(m³ D)⁻¹ was achieved for Fe-COF_BTC under optimized condition. The massively produced Fe-COF_BTC presented good solubility in alkaline and polar organic solvents, thus allow to process as homogeneous or heterogenous electrocatalyst for oxygen reduction reaction. The catalyst exhibited good performance of 0.79 V (vs. RHE, half-wave) and >95% recovery in homogeneous electroreduction of O₂ in 0.1 M KOH. A superior performance of 0.86 V was achieved by sol–gel-like processing of Fe-COF_BTC on carbon paper due to the enhanced conductivity. The scale-up soluble catalysts with uniform properties provide more opportunities for practical applications of COF_BTC.

中文翻译：

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HiGee 大规模合成可溶性共价有机框架的策略

具有均匀结构和性能的共价有机框架（COF）的放大合成对其实际应用具有重要意义。在这里，我们提出了一种通过高重力强化合成大量生产类酞菁 COF (COF _{BTC ) 的简便方法。发现醇类溶剂和碱性催化剂可协同改善 COF BTC}的形成。高浓度和高反应温度也有利于高产。高重力下强化的传质和传热促进了具有均匀结构和性能的 COF _BTC的放大。_{Fe-COF BTC}实现了305.9 kg∙(m ³  D) ⁻¹的高时空产率优化条件下。大量生产的 Fe-COF _BTC在碱性和极性有机溶剂中具有良好的溶解性，因此可以作为均相或多相电催化剂进行氧还原反应。_{该催化剂在 0.1 M KOH 中的 O 2}均相电还原中表现出 0.79 V（相对于 RHE，半波）和 >95% 回收率的良好性能。由于增强的导电性，通过类溶胶凝胶处理 Fe-COF _{BTC在碳纸上实现了 0.86 V 的优异性能。}性能均匀的可溶性催化剂的放大为COF _BTC的实际应用提供了更多机会。