当前位置: X-MOL 学术Environ. Health Perspect. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Residential Wood Burning and Pulmonary Function in the Agricultural Lung Health Study
Environmental Health Perspectives ( IF 10.4 ) Pub Date : 2022-8-25 , DOI: 10.1289/ehp10734
Julie D White 1, 2 , Annah B Wyss 1 , Thanh T Hoang 1 , Mikyeong Lee 1 , Marie Richards 3 , Christine G Parks 1 , Laura E Beane-Freeman 4 , John L Hankinson 5 , David M Umbach 6 , Stephanie J London 1, 7
Affiliation  

Abstract

Background:

In low- and middle-income countries, burning biomass indoors for cooking or heating has been associated with poorer lung function. In high-income countries, wood, a form of biomass, is commonly used for heating in rural areas with increasing prevalence. However, in these settings the potential impact of chronic indoor woodsmoke exposure on pulmonary function is little studied.

Objective:

We evaluated the association of residential wood burning with pulmonary function in case–control study of asthma nested within a U.S. rural cohort.

Methods:

Using sample weighted multivariable linear regression, we estimated associations between some and frequent wood burning, both relative to no exposure, in relation to forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), their ratio (FEV1/FVC), and fractional exhaled nitric oxide (FeNO). We examined effect modification by smoking or asthma status.

Results:

Among all participants and within smoking groups, wood burning was not appreciably related to pulmonary function. However, in individuals with asthma (n=1,083), frequent wood burning was significantly associated with lower FEV1 [β: 164mL; 95% confidence interval (CI): 261, 66mL], FVC (β: 125mL; 95% CI: 230, 20mL), and FEV1/FVC (β: 2%; 95% CI: 4, 0.4%), whereas no appreciable association was seen in individuals without asthma (n=1,732). These differences in association by asthma were statistically significant for FEV1 (pinteraction=0.0044) and FEV1/FVC (pinteraction=0.049). Frequent wood burning was also associated with higher FeNO levels in all individuals (n=2,598; β: 0.1 ln(ppb); 95% CI: 0.02, 0.2), but associations did not differ by asthma or smoking status.

Discussion:

Frequent exposure to residential wood burning was associated with a measure of airway inflammation (FeNO) among all individuals and with lower pulmonary function among individuals with asthma. This group may wish to reduce wood burning or consider using air filtration devices. https://doi.org/10.1289/EHP10734



中文翻译:

农业肺健康研究中的住宅木材燃烧和肺功能

摘要

背景:

在低收入和中等收入国家,在室内燃烧生物质做饭或取暖与肺功能较差有关。在高收入国家,木材(一种生物质形式)通常用于农村地区的取暖,而且普及率越来越高。然而,在这些环境中,长期室内木烟暴露对肺功能的潜在影响鲜有研究。

客观的:

我们在美国农村队列中的哮喘病例对照研究中评估了住宅木材燃烧与肺功能的关联。

方法:

使用样本加权多元线性回归,我们估计了一些和频繁的木材燃烧之间的关联,两者都相对于没有暴露,与 1 秒内的用力呼气量有关(FEV1)、用力肺活量 (FVC)、它们的比值 (FEV1/FVC) 和部分呼出气一氧化氮 (FeNO)。我们检查了吸烟或哮喘状态对效果的影响。

结果:

在所有参与者和吸烟组中,木材燃烧与肺功能没有明显关系。然而,在哮喘患者中(n=1,083),频繁的木材燃烧与较低的FEV1[β-164毫升; 95% 置信区间 (CI):-261,-66毫升],FVC(β-125毫升; 95% 置信区间:-230,-20毫升), 和FEV1/FVC(β-2%; 95% 置信区间:-4,-0.4%),而在没有哮喘的个体中没有观察到明显的关联(n=1,732)。这些与哮喘相关的差异具有统计学意义FEV1(p一世ner一个C一世n=0.0044) 和FEV1/FVC(p一世ner一个C一世n=0.049)。频繁的木材燃烧也与所有个体较高的 FeNO 水平有关(n=2,598;β0.1 ln(ppb); 95% CI:0.02, 0.2),但相关性并未因哮喘或吸烟状况而异。

讨论:

频繁暴露于住宅木材燃烧与所有个体的气道炎症 (FeNO) 测量以及哮喘患者的肺功能降低有关。该组可能希望减少木材燃烧或考虑使用空气过滤装置。https://doi.org/10.1289/EHP10734

更新日期:2022-08-25
down
wechat
bug