Purpose: Rigorous adaptation methods are needed to revise existing evidence-based behavioral interventions for implementation for new target populations, revised/updated outcomes, new delivery modalities, recent advances, and new technologies. We describe an adaptation method designed to overcome the real-world challenges of having very limited existing expertise, resources, and time. Method: This adaptation method and accompanying visualization tool (“Deconstruction/Reconstruction Matrix”) preserves theoretical mechanisms of behavior change, accounts for challenges in utilizing new technologies, and strengthens clinical processes, with an emphasis on safety. Results: The adaptation of an in-person HIV behavioral intervention for sexual and gender diverse men in Kazakhstan to one delivered remotely via telecommunication and social media technologies exemplifies the process and strengths of the method, concomitantly resulting in recommendations for adaptation and implementation of mobile health (mHealth) and digital health interventions. Discussion: This method allows researchers and clinicians to adapt interventions rapidly and rigorously and to benefit from new technologies.

目的：需要严格的适应方法来修订现有的基于证据的行为干预措施，以实施新的目标人群、修订/更新的结果、新的交付方式、最新进展和新技术。我们描述了一种适应方法，旨在克服现实世界中现有专业知识、资源和时间非常有限的挑战。方法：这种适应方法和随附的可视化工具（“解构/重建矩阵”）保留了行为改变的理论机制，解释了利用新技术的挑战，并加强了临床过程，并强调安全性。结果：哈萨克斯坦针对性和性别多样化男性的面对面艾滋病毒行为干预调整为通过电信和社交媒体技术远程提供的干预措施，体现了该方法的流程和优势，同时提出了关于调整和实施移动医疗的建议（移动医疗）和数字健康干预措施。讨论：这种方法使研究人员和临床医生能够快速、严格地调整干预措施，并从新技术中受益。