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Detection of Global Brain Injury Using Point-of-Care Neonatal MRI Scanner
Neuropediatrics ( IF 1.4 ) Pub Date : 2023-01-19 , DOI: 10.1055/a-1926-2238
Alona Bin-Nun 1, 2 , Yair Kasirer 1 , Nadeen Abu-Ata 3 , Debra Rosenbaum 1 , Ruth Cytter-Kuint 2 , Cathy Hammerman 1, 2 , Eliel Ben-David 2, 3
Affiliation  

Background Conventional magnetic resonance imaging (MRI) neuroimaging of infants is complicated by the need to transport infants outside the neonatal intensive care unit (NICU), often to distant areas of the hospital. Primary Objective The main aim of this study was to evaluate and compare scoring of images from a novel 1T MRI, which enables neuroimaging within the NICU, with those from a conventional MRI. Secondary Objective The second aim of this study was to document improved expediency, and thereby greater patient safety, as reflected by decreased transport time. Materials and Methods Thirty premature infants (mean gestational age: 28.8 ± 2.1 weeks) were scanned consecutively on the novel 1T and 1.5T conventional scanners at term-equivalent age. Orthogonal T1- and T2-weighted images were acquired and reviewed. A global brain abnormality score (Kidokoro) was assigned independently to all images by two radiologists. Interrater agreement was evaluated using the kappa statistic and interscanner agreement was evaluated by Bland–Altman analysis. Transport time to and from both scanners was monitored and compared. Results Weighted kappas were 0.77 (standard error of measurement [SEM] 0.08; confidence interval [CI]: 0.62–0.92) and 0.86 (SEM: 0.07; CI: 0.73–1), for the 1T and 1.5T scanners, respectively, reflecting substantial interrater agreement. Bland–Altman analysis showed excellent agreement between the two scanners.Transport time was 8 ± 6 minutes for the 1T MRI versus 46 ± 21 minutes for the conventional MRI (p < 0.00001). No adverse events were recorded during transport. Standard transport times will vary from institution to institution. Conclusions Kidokoro scores are similar when comparing images obtained from a 1T MRI with those of a conventional 1.5T MRI, reflecting comparable image quality. Transport time was significantly decreased using the 1T neonatal MRI.

中文翻译:

使用护理点新生儿 MRI 扫描仪检测整体脑损伤

背景 由于需要将婴儿运送到新生儿重症监护病房 (NICU) 之外(通常是医院的偏远地区),传统的婴儿磁共振成像 (MRI) 神经成像变得复杂。主要目的 本研究的主要目的是评估和比较新型 1T MRI 的图像评分与传统 MRI 的图像评分,该 1T MRI 能够在 NICU 内进行神经成像。次要目标 本研究的第二个目标是记录改进的便利性,从而提高患者的安全性,这体现在运输时间的减少上。材料和方法 30 名早产儿(平均胎龄:28.8 ± 2.1 周)在新型 1T 和 1.5T 传统扫描仪上以足月当量年龄连续扫描。获取并审查正交 T1 和 T2 加权图像。由两名放射科医生独立为所有图像分配全局大脑异常评分(Kidokoro)。使用 kappa 统计量评估评估者间的一致性,并通过 Bland-Altman 分析评估扫描仪间的一致性。对往返两个扫描仪的运输时间进行了监控和比较。结果 1T 和 1.5T 扫描仪的加权 kappas 分别为 0.77(测量标准误差 [SEM] 0.08;置信区间 [CI]:0.62–0.92)和 0.86(SEM:0.07;CI:0.73–1),反映实质性的参与者间协议。Bland-Altman 分析显示两台扫描仪之间的一致性非常好。1T MRI 的传输时间为 8 ± 6 分钟,而传统 MRI 的传输时间为 46 ± 21 分钟(p < 0.00001)。运输过程中未记录任何不良事件。标准交通时间因机构而异。结论 将 1T MRI 获得的图像与传统 1.5T MRI 获得的图像进行比较时,Kidokoro 评分相似,反映出图像质量相当。使用 1T 新生儿 MRI 显着减少了转运时间。
更新日期:2023-01-20
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