The dissolving microneedle loading vasodilatorTOP-M119 (M119) penetrates the scalp and releases the drug to the blood vessels. TheM119 drug induces vasodilation and angiogenesis, and it causes vascularization around hair follicles supplying oxygen and nutrients. This mode of action of M119 drug finally affects alopecia hair follicles' conversion to anagen and hair growth. This is reported by Hyungil Jung and co-workers in article number 2200052.

中文翻译：

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双模式血管扩张剂 M119 通过溶解微针递送至毛囊用于高级脱发治疗 (Adv. Therap. 8/2022)

溶解性微针加载血管扩张剂TOP-M119（M119）穿透头皮并将药物释放到血管中。M119 药物诱导血管舒张和血管生成，并引起毛囊周围的血管形成，从而提供氧气和营养。M119药物的这种作用方式最终影响脱发毛囊向生长期和毛发生长的转化。Hyungil Jung 及其同事在文章编号 2200052 中对此进行了报道。