Purpose

To investigate the value of contrast-enhanced motion-sensitized driven equilibrium (MSDE) based black blood three-dimensional (3D) turbo spin echo (TSE) sequence in the detection of brain metastases compared with 3D Turbo Field Echo (TFE) sequence.

Material and methods

53 patients with suspected brain metastases were included in this study between November 2021 and February 2022. Contrast-enhanced cranial 3D TFE and MSDE-based 3D black blood TSE MR imaging were performed for each patient. Two senior neuroradiologists independently evaluated all contrast-enhanced 3D TFE and 3D black blood TSE images to detect brain metastases. The images were divided into two groups: the TFE group and the black blood TSE group. Agreement between the two reviewers for detection of the brain metastases in each group was performed using the kappa test. The two reviewers determined the final result for brain metastasis in the two groups by consensus. A paired t-test was performed for the final detection of brain metastases between the black blood TSE group and the TFE group.

Results

There was a very good agreement between the two reviewers for the TSE group (kappa = 0.823) and a good agreement for the TFE group (kappa = 0.663). There was a statistical difference in the detection of small cortical and subcortical metastases between the TFE and the black blood TSE groups (t = 5.039, P = 0.000 < 0.05). There was no statistical difference in the detection of small supratentorial deep lesions and subtentorial lesions between the two groups.

Conclusion

Compared with conventional 3D TFE sequence, MSDE-based black blood 3D TSE sequence was superior for visualizing small brain metastases, especially small cortical and subcortical metastases.

中文翻译：

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基于动敏驱动平衡的黑血3D TSE序列在脑转移瘤检测中的应用

目的

与 3D 涡轮场回波 (TFE) 序列相比，研究基于对比增强运动敏化驱动平衡 (MSDE) 的黑血三维 (3D) 涡轮自旋回波 (TSE) 序列在检测脑转移中的价值。

材料与方法

2021 年 11 月至 2022 年 2 月期间，53 名疑似脑转移患者被纳入本研究。对每位患者进行了对比增强颅骨 3D TFE 和基于 MSDE 的 3D 黑血 TSE MR 成像。两位高级神经放射学家独立评估了所有对比增强的 3D TFE 和 3D 黑血 TSE 图像以检测脑转移。图像分为两组：TFE 组和黑血 TSE 组。两位评价者就每组脑转移的检测达成一致，使用 kappa 检验进行。两位评价者协商一致确定两组脑转移的最终结果。对黑血 TSE 组和 TFE 组之间的脑转移进行了配对t检验。

结果

TSE 组 (kappa = 0.823) 和 TFE 组 (kappa = 0.663) 的两位评审员之间达成了很好的一致。TFE 组和黑血 TSE 组之间小皮质和皮质下转移的检测存在统计学差异（t  = 5.039，P  = 0.000 < 0.05）。两组间小的幕上深部病灶和幕下病灶检出率无统计学差异。

结论

与传统的 3D TFE 序列相比，基于 MSDE 的黑血 3D TSE 序列在可视化小脑转移瘤方面具有优势，尤其是小的皮质和皮质下转移灶。