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Rapid Increase in Suspected SARS-CoV-2 Reinfections, Clark County, Nevada, USA, December 2021
Emerging Infectious Diseases ( IF 11.8 ) Pub Date : 2022-08-15 , DOI: 10.3201/eid2810.221045
Jeanne Ruff , Ying Zhang , Matthew Kappel , Sfurti Rathi , Kellie Watkins , Lei Zhang , Cassius Lockett

Genetic differences between SARS-CoV-2 variants raise concerns about reinfection. Public health authorities monitored the incidence of suspected reinfection in Clark County, Nevada, USA, during March 2020–March 2022. Suspected reinfections, defined as a second positive PCR test collected >90 days after an initial positive test, were monitored through an electronic disease surveillance system. We calculated the proportion of all new cases per week that were suspected reinfections and rates per 1,000 previously infected persons by demographic groups. The rate of suspected reinfection remained <2.7% until December 2021, then increased to ≈11%, corresponding with local Omicron variant detection. Reinfection rates were higher among adults 18–50 years of age, women, and minority groups, especially persons identifying as American Indian/Alaska Native. Suspected reinfection became more common in Clark County after introduction of the Omicron variant, and some demographic groups are disproportionately affected. Public health surveillance could clarify the SARS-CoV-2 reinfection burden in communities.



中文翻译:

疑似 SARS-CoV-2 再感染人数迅速增加,美国内华达州克拉克县,2021 年 12 月

SARS-CoV-2 变体之间的遗传差异引起了对再感染的担忧。公共卫生当局监测了 2020 年 3 月至 2022 年 3 月期间美国内华达州克拉克县疑似再感染的发生率。疑似再感染定义为在首次阳性检测后 > 90 天收集的第二次阳性 PCR 检测,通过电子疾病监测监控系统。我们计算了每周所有新病例中疑似再感染的比例和每 1,000 名先前感染者的比率(按人口统计群体)。疑似再感染率保持<2.7% 到 2021 年 12 月,然后增加到 ≈11%,与本地 Omicron 变异检测相对应。在 18-50 岁的成年人、女性和少数群体中,再感染率更高,尤其是美洲印第安人/阿拉斯加原住民。在引入 Omicron 变体后,疑似再感染在克拉克县变得更加普遍,一些人口群体受到的影响尤为严重。公共卫生监测可以澄清社区中 SARS-CoV-2 再感染的负担。

更新日期:2022-08-16
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