BACKGROUND AND OBJECTIVES Evidence suggests that children and adolescents with avoidant/restrictive food intake disorder (ARFID) have heterogeneous clinical presentations. To use latent class analysis (LCA) and determine the frequency of various classes in pediatric patients with ARFID drawn from a 2-year surveillance study. METHODS Cases were ascertained using the Canadian Pediatric Surveillance Program methodology from January 1, 2016, to December 31, 2017. An exploratory LCA was undertaken with latent class models ranging from 1 to 5 classes. RESULTS Based on fit statistics and class interpretability, a 3-class model had the best fit: Acute Medical (AM), Lack of Appetite (LOA), and Sensory (S). The probability of being classified as AM, LOA, and S was 52%, 40.7%, and 6.9%, respectively. The AM class was distinct for increased likelihood of weight loss (92%), a shorter length of illness (<12 months) (66%), medical hospitalization (56%), and heart rate <60 beats per minute (31%). The LOA class was distinct for failure to gain weight (97%) and faltering growth (68%). The S class was distinct for avoiding certain foods (100%) and refusing to eat because of sensory characteristics of the food (100%). Using posterior probability assignments, a mixed group AM/LOA (n = 30; 14.5%) had characteristics of both AM and LOA classes. CONCLUSIONS This LCA suggests that ARFID is a heterogeneous diagnosis with 3 distinct classes corresponding to the 3 subtypes described in the literature: AM, LOA, and S. The AM/LOA group had a mixed clinical presentation. Clinicians need to be aware of these different ARFID presentations because clinical and treatment needs will vary.

中文翻译：

---

患有回避/限制性食物摄入障碍的儿童和青少年的分类。

背景和目的 有证据表明，患有回避/限制性食物摄入障碍 (ARFID) 的儿童和青少年具有异质的临床表现。使用潜在类别分析 (LCA) 并确定来自 2 年监测研究的 ARFID 儿科患者的各种类别的频率。方法 从 2016 年 1 月 1 日到 2017 年 12 月 31 日，使用加拿大儿科监测计划方法确定病例。使用 1 到 5 个类别的潜在类别模型进行探索性 LCA。结果基于拟合统计和类可解释性，3 类模型具有最佳拟合：急性医学 (AM)、食欲不振 (LOA) 和感官 (S)。被分类为 AM、LOA 和 S 的概率分别为 52%、40.7% 和 6.9%。AM 类别在体重减轻（92%）、病程较短（<12 个月）（66%）、住院治疗（56%）和心率 <60 次 / 分钟（31%）的可能性上有所不同. LOA 类别因体重增加失败 (97%) 和生长迟缓 (68%) 而不同。S 类在避免某些食物 (100%) 和因食物的感官特征而拒绝进食 (100%) 方面是不同的。使用后验概率分配，混合组 AM/LOA（n = 30；14.5%）具有 AM 和 LOA 类的特征。结论 该 LCA 表明 ARFID 是一种异质诊断，具有 3 个不同的类别，对应于文献中描述的 3 种亚型：AM、LOA 和 S。AM/LOA 组具有混合的临床表现。