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Experimental Infection of Peromyscus Species Rodents with Sin Nombre Virus
Emerging Infectious Diseases ( IF 11.8 ) Pub Date : 2022-08-10 , DOI: 10.3201/eid2809.222509
Kaye Quizon, Kimberly Holloway, Mahmood Iranpour, Bryce M. Warner, Yvon Deschambault, Geoff Soule, Kevin Tierney, Darwyn Kobasa, Angela Sloan, David Safronetz

We demonstrate that 6 distinct Peromyscus rodent species are permissive to experimental infection with Sin Nombre orthohantavirus (SNV). Viral RNA and SNV antibodies were detected in members of all 6 species. P. leucopus mice demonstrated markedly higher viral and antibody titers than P. maniculatus mice, the established primary hosts for SNV.



中文翻译:

Sin Nombre 病毒对 Peromyscus 种啮齿动物的实验感染

我们证明 6 种不同的Peromyscus啮齿动物物种允许实验性感染 Sin Nombre Orthohantavirus (SNV)。在所有 6 个物种的成员中检测到病毒 RNA 和 SNV 抗体。P. leucopus小鼠的病毒和抗体滴度明显高于P. maniculatus小鼠后者是 SNV 的主要宿主。

更新日期:2022-08-11
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