The prevalence of long-term postoperative sensorimotor deficits in children undergoing perirolandic resective epilepsy surgery is unclear. The risk of developing these deficits must be weighed against the potential reduction in seizure frequency after surgery. In this study, the authors investigated the prevalence of sensorimotor deficits after resective surgery at ≥ 1 year postoperatively.

A systematic review and individual patient data meta-analysis was conducted using PubMed, Embase, and Scopus databases. Subgroups of patients were identified and categorized according to their outcomes as follows: group A patients were denoted as seizure free with no postoperative sensorimotor deficits; group B patients experienced seizure recurrence with no deficit; group C patients were seizure free with deficits; and group D patients were not seizure free and with deficits. Rates of sensory deficits were examined in patients undergoing postcentral gyrus resection, and rates of motor deficits were aggregated in patients undergoing precentral gyrus resection.

Of 797 articles resulting from the database searches, 6 articles including 164 pediatric patients at a mean age of 7.7 ± 5.2 years with resection for drug-resistant perirolandic epilepsy were included in the study. Seizure freedom was observed in 118 (72.9%) patients at a mean follow-up of 3.4 ± 1.8 years. In total, 109 (66.5%) patients did not develop sensorimotor deficits at last follow-up, while 55 (33.5%) had permanent deficits. Ten (14.3%) of 70 patients with postcentral gyrus resection had permanent sensory deficits. Of the postcentral gyrus resection patients, 41 (58.6%) patients were included in group A, 19 (27.1%) in group B, 7 (10.0%) in group C, and 3 (4.3%) in group D. Forty (37.7%) of 106 patients with precentral resections had permanent motor deficits. Of the precentral gyrus resection patients, 50 (47.2%) patients were in group A, 16 (15.1%) in group B, 24 (22.6%) in group C, and 16 (15.1%) in group D. Patients without focal cortical dysplasia were more likely to have permanent motor deficits relative to those with focal cortical dysplasia in the precentral surgery cohort (p = 0.02).

In total, 58.6% of patients were seizure free without deficit, 27.1% were not seizure free and without deficit, 10.0% were seizure free but with deficit, and 4.3% were not seizure free and with deficit. Future studies with functional and quality-of-life data, particularly for patients who experience seizure recurrence with no deficits (as in group B in the present study) and those who are seizure free with deficits (as in group C) after treatment, are necessary to guide surgical decision-making.

接受perirolandic切除性癫痫手术的儿童长期术后感觉运动障碍的患病率尚不清楚。必须权衡发生这些缺陷的风险与手术后癫痫发作频率的潜在降低。在这项研究中，作者调查了术后≥ 1 年切除手术后感觉运动障碍的发生率。

使用 PubMed、Embase 和 Scopus 数据库进行系统回顾和个体患者数据荟萃分析。患者亚组根据他们的结果被识别和分类如下：A组患者被称为无癫痫发作，没有术后感觉运动障碍；B组患者癫痫发作复发，无缺损；C组患者无癫痫发作，有缺陷；D 组患者并非无癫痫发作且有缺陷。在接受中央回切除术的患者中检查感觉障碍的发生率，并在接受中央回切除术的患者中汇总运动障碍的发生率。

从数据库搜索得到的 797 篇文章中，6 篇文章包括 164 名平均年龄为 7.7 ± 5.2 岁且因耐药性周围癫痫手术切除的儿科患者。平均随访 3.4 ± 1.8 年，118 名 (72.9%) 患者无癫痫发作。总共有 109 名 (66.5%) 患者在最后一次随访中没有出现感觉运动障碍，而 55 名 (33.5%) 患者有永久性缺陷。70 名接受中央回切除术的患者中有 10 名（14.3%）有永久性感觉障碍。中央回切除术后患者中，A组41例（58.6%），B组19例（27.1%），C组7例（10.0%），D组3例（4.3%）。 40例（37.7 %) 的 106 名中央前切除患者中存在永久性运动障碍。中央前回切除患者中，A组50例（47.2%），

总体而言，58.6% 的患者无癫痫发作且无功能障碍，27.1% 的患者无癫痫发作且无功能障碍，10.0% 的患者无癫痫发作但有功能障碍，4.3% 的患者并非无癫痫发作且有功能障碍。未来关于功能和生活质量数据的研究，特别是对于没有癫痫发作复发且无缺陷的患者（如本研究中的 B 组）和治疗后无癫痫发作但有缺陷的患者（如 C 组），是有必要指导手术决策。