Structures of the endogenous peptide- and selective non-peptide agonist-bound SSTR2 signaling complexes.,Cell Research

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Structures of the endogenous peptide- and selective non-peptide agonist-bound SSTR2 signaling complexes.
Cell Research ( IF 44.1 ) Pub Date : 2022-05-16 , DOI: 10.1038/s41422-022-00669-z
Li-Nan Chen _{1,

2,

3} , Wei-Wei Wang ₄ , Ying-Jun Dong ₁ , Dan-Dan Shen ₁ , Jia Guo ₁ , Xuefei Yu ₅ , Jiao Qin ₁ , Su-Yu Ji ₁ , Huibing Zhang ₁ , Qingya Shen ₁ , Qiaojun He ₆ , Bo Yang ₆ , Yan Zhang _{1,

3,

4,

7,

8} , Qinglin Li ₅ , Chunyou Mao _{2,

3}

Affiliation

Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University, School of Medicine, Hangzhou, Zhejiang, China.
Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Center for Structural Pharmacology and Therapeutics Development, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, Zhejiang, China.
The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, Zhejiang, China.
Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China.
MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Zhejiang Provincial Key Laboratory of Immunity and Inflammatory diseases, Hangzhou, Zhejiang, China.