Fibroblasts strongly impact tumor progression, but whether they prime the pre-metastatic niche is poorly understood. In this issue of Immunity, Gong and Li et al. identify lung-specific immunosuppressive fibroblasts, which are hijacked by breast cancer cells to facilitate metastasis.

中文翻译：

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肺成纤维细胞作为乳腺癌转移的“土壤肥料”

成纤维细胞强烈影响肿瘤进展，但它们是否引发转移前生态位尚不清楚。在本期Immunity中，龚和李等人。识别肺特异性免疫抑制成纤维细胞，这些成纤维细胞被乳腺癌细胞劫持以促进转移。