Climate change-related disasters have drawn increased attention to the impact of air pollution on health. 122 children ages 9–11 years old, M(SD) = 9.91(.56), participated. Levels of particulate matter (PM2.5) near participants’ homes were obtained from the Environmental Protection Agency. Cytokines were assayed from 100 child serum samples: IL-6, IL-8, IL-10, and TNFα. Autonomic physiology was indexed by pre-ejection period (PEP), respiratory sinus arrhythmia (RSA), cardiac autonomic regulation (CAR), and cardiac autonomic balance (CAB). IL-6 was positively related to daily PM2.5 (r = .26, p = .009). IL-8 was negatively associated with monthly PM2.5 (r = −.23, p = .02). PEP was positively related to daily (r = .29, p = .001) and monthly PM2.5 (r = .18, p = .044). CAR was negatively associated with daily PM2.5 (r = −.29, p = .001). IL-10, TNFα, RSA, and CAB were not associated with PM2.5. Air pollution may increase risk of inflammation in children.

中文翻译：

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空气污染与儿童外周炎症和心脏自主生理学的关系

与气候变化有关的灾害引起了人们对空气污染对健康影响的更多关注。122 名 9-11 岁的儿童，M ( SD ) = 9.91(.56) 参加了比赛。参与者家附近的颗粒物 (PM2.5) 水平来自环境保护局。从 100 个儿童血清样本中检测细胞因子：IL-6、IL-8、IL-10 和 TNFα。自主生理学由射血前期 (PEP)、呼吸性窦性心律失常 (RSA)、心脏自主调节 (CAR) 和心脏自主平衡 (CAB) 进行索引。IL-6 与每日 PM2.5 呈正相关（r  = .26，  p = .009）。IL-8 与每月 PM2.5 呈负相关 ( r = -.23, p= .02)。PEP 与每日 ( r = .29, p = .001) 和每月 PM2.5 ( r = .18, p = .044) 呈正相关。CAR 与每日 PM2.5 呈负相关（r = -.29，p = .001）。IL-10、TNFα、RSA 和 CAB 与 PM2.5 无关。空气污染可能会增加儿童炎症的风险。