Cementum regeneration was regarded as the critical goal for periodontal regeneration, and M2 macrophage-based therapy was expected to be a promising strategy. However, little is known about the effects of M2 macrophages on cementoblast mineralization and tropism, especially under inflammation. Here we investigated for the first time the crosstalk between M2 macrophages and Porphyromonas gingivalis (Pg)-stimulated cementoblasts.

中文翻译：

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具有炎症趋向性的 M2 巨噬细胞促进成牙骨质细胞矿化

牙骨质再生被认为是牙周再生的关键目标，基于 M2 巨噬细胞的治疗有望成为一种有前途的策略。然而，人们对 M2 巨噬细胞对成牙骨质细胞矿化和趋向性的影响知之甚少，尤其是在炎症条件下。在这里，我们首次研究了 M2 巨噬细胞和牙龈卟啉单胞菌( Pg ) 刺激的成牙骨质细胞之间的串扰。