Although researchers have been exploring therapeutic strategies of treating serious periodontal tissue loss, including the application of stem cells, tissue regeneration of the periodontal complex involving cementum, periodontium, and alveolar bone has hardly been achieved. Aiming at tackling the problem of severely damaged periodontal complex, it is worth trying to make advantages of Hertwig's epithelial root sheath (HERS) cells to tissue regeneration mimicking the physiological developmental process with their ability of cementum, bone, and periodontium formation.

中文翻译：

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Hertwig 的上皮根鞘细胞显示出牙周复合体再生的潜力

尽管研究人员一直在探索治疗严重牙周组织缺失的治疗策略，包括干细胞的应用，但涉及牙骨质、牙周组织和牙槽骨的牙周复合体的组织再生几乎没有实现。针对牙周复合体严重受损的问题，利用赫特维格上皮根鞘（HERS）细胞具有形成牙骨质、骨和牙周组织的能力，模拟生理发育过程进行组织再生，值得尝试。