Background: Administration of the Einstein Neonatal Neurobehavioral Assessment Scale (ENNAS) can be time-consuming, and items can be highly correlated. We aimed to determine: (1) its factor analytic structure; (2) the validity of the factor structure; and (3) the associations of physiologic measures with factor scores. Methods: A factor analysis reduced 21 ENNAS items into 5 factors in 57 congenital heart disease (CHD) and 35 healthy infants. Multiple linear regressions examined the association of factor scores with group, gestational age, and physiologic variables. Results: 5-factor solution: 1 (Orienting Reflex), 2 (Extensor Axial Tone), 3 (Primitive Reflexes), 4 (Flexor Tone), 5 (Reflexive Tone Around Extremity Joints). Moderate to strong evidence supported: face, discriminant, and construct validity of these factors, with Factor 2 having the strongest. Conclusions: Components of Factor 2 may provide similar information about neonatal development, thus reducing the time for and burden of administration for researchers and clinicians.

背景：爱因斯坦新生儿神经行为评估量表 (ENNAS) 的管理可能很耗时，并且项目可能高度相关。我们旨在确定：（1）其因子分析结构；（2）因子结构的有效性；(3) 生理指标与因子得分的关联。方法：对 57 名先天性心脏病 (CHD) 和 35 名健康婴儿进行因子分析，将 21 个 ENNAS 项目归为 5 个因子。多元线性回归检查了因子评分与组、胎龄和生理变量的关联。结果：5 因素解决方案：1（定向反射）、2（伸肌轴向张力）、3（原始反射）、4（屈肌张力）、5（四肢关节周围的反射张力）。支持中等到强有力的证据：这些因素的面子效度、判别效度和结构效度，其中因子 2 的效度最强。结论：因子 2 的成分可以提供有关新生儿发育的类似信息，从而减少研究人员和临床医生的给药时间和负担。