A hallmark of ARDS is progressive shrinking of the ‘baby lung,’ now referred to as the ventilator-induced lung injury (VILI) ‘vortex.’ Reducing the risk of the VILI vortex is the goal of current ventilation strategies; unfortunately, this goal has not been achieved nor has mortality been reduced. However, the temporal aspects of a mechanical breath have not been considered. A brief expiration prevents alveolar collapse, and an extended inspiration can recruit the atelectatic lung over hours. Time-controlled adaptive ventilation (TCAV) is a novel ventilator approach to achieve these goals, since it considers many of the temporal aspects of dynamic lung mechanics.

中文翻译：

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缩小婴儿肺以平息 VILI 漩涡

ARDS 的一个标志是“婴儿肺”的逐渐缩小，现在被称为呼吸机引起的肺损伤 (VILI) 的“漩涡”。降低 VILI 涡流的风险是当前通风策略的目标；不幸的是，这个目标没有实现，死亡率也没有降低。然而，尚未考虑机械呼吸的时间方面。短暂的呼气可以防止肺泡塌陷，而长时间的吸气可以在数小时内恢复肺不张。时间控制的自适应通气 (TCAV) 是实现这些目标的一种新型呼吸机方法，因为它考虑了动态肺力学的许多时间方面。