Diagnostic Code-Based Screening for Identifying Children with Primary Hyperoxaluria.,The Journal of Urology

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Diagnostic Code-Based Screening for Identifying Children with Primary Hyperoxaluria.
The Journal of Urology ( IF 6.6 ) Pub Date : 2022-08-05 , DOI: 10.1097/ju.0000000000002863
Gregory Tasian _{1,

2} , Kimberley Dickinson ₃ , John Karafilidis ₄ , Nicole Marchesani ₃ , Nuno Antunes ₄ , Hanieh Razzaghi ₃ , Levon Utidjian ₃ , Karyn Yonekawa ₅ , Doug Coplen ₆ , Samina Muneeruddin ₇ , Bob DeFoor ₈ , Kyle O Rove ₉ , Christopher Forrest ₃ , Christina Ching ₁₀

Affiliation

Department of Surgery, Division of Urology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Applied Clinical Research Center, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Dicerna Pharmaceuticals, Cambridge, Massachusetts.
Department of Pediatrics, Division of Nephrology, Seattle Children's Hospital, Seattle, Washington.
Department of Surgery, Division of Urology, St. Louis Children's Hospital, St. Louis, Missouri.
Department of Pediatrics, Division of Nephrology, AI DuPont Children's Hospital, Wilmington, Delaware.
Department of Surgery, Division of Urology, Cincinnati Children's Hospital and Medical Center, Cincinnati, Ohio.
Department of Surgery, Division of Urology, Children's Hospital Colorado, Aurora, Colorado.
Department of Pediatric Urology, Nationwide Children's Hospital, Columbus, Ohio.

We evaluated the utility of diagnostic codes to screen for patients with primary hyperoxaluria (PH) and evaluate their positive predictive value (PPV) in identifying children with this rare condition in PEDSnet, a clinical research network of pediatric health systems that shares electronic health records data.

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