Incisional negative pressure wound therapy (iNPWT) has shown effectiveness in the treatment of high-risk surgical wounds. Especially patients with diabetes-induced peripheral arterial disease undergoing major limb amputation have a high intrinsic risk for post-surgical wound infections. While normal gauze wound dressings do not cause stimulation of microvasculature, iNPWT might improve wound healing and reduce wound complications. The purpose of this study was to systematically review the literature for rates of wound complications and readmissions, as well as post-surgical 30-day mortality.

中文翻译：

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切口负压伤口治疗减少主要截肢手术部位感染：荟萃分析。

切口负压伤口治疗（iNPWT）在治疗高危手术伤口方面已显示出有效性。尤其是患有糖尿病引起的外周动脉疾病并接受大截肢的患者，术后伤口感染的内在风险很高。虽然普通纱布伤口敷料不会刺激微血管系统，但 iNPWT 可能会改善伤口愈合并减少伤口并发症。本研究的目的是系统回顾有关伤口并发症和再入院率以及术后 30 天死亡率的文献。