An attractive, versatile, and operationally simple, visible-light-induced, transition-metal-free, photocatalyst-free, and oxidant-free trifluoromethylation has been demonstrated. Triflic anhydride (Tf₂O), being inexpensive and readily available, was chosen as the radical trifluoromethyl source. Thianthrene was used as a recyclable Tf₂O-activating reagent, and a high-yielding and scalable trifluoromethylation reaction was achieved. Density functional theory and mechanistic studies showed that a free radical homolytic process excited by visible light is involved in this reaction, generating a key trifluoromethyl radical intermediate.

中文翻译：

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可见光诱导的无自由基三氟甲基化

已经证明了一种有吸引力的、多功能的、操作简单的、可见光诱导的、无过渡金属、无光催化剂和无氧化剂的三氟甲基化。三氟甲磺酸酐 (Tf ₂ O) 便宜且容易获得，被选为自由基三氟甲基源。噻蒽被用作可回收的 Tf ₂ O 活化剂，实现了高产和可扩展的三氟甲基化反应。密度泛函理论和机理研究表明，可见光激发的自由基均裂过程参与了该反应，产生了关键的三氟甲基自由基中间体。