Associations of dual sensory impairment with long-term depressive and anxiety symptoms in the United States,Journal of Affective Disorders

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Associations of dual sensory impairment with long-term depressive and anxiety symptoms in the United States
Journal of Affective Disorders ( IF 6.6 ) Pub Date : 2022-08-03 , DOI: 10.1016/j.jad.2022.07.067
Nicole M Armstrong ₁ , Camila Vieira Ligo Teixeira ₂ , Colby Gendron ₃ , Willa D Brenowitz ₄ , Frank R Lin ₅ , Bonnelin Swenor ₆ , Danielle S Powell ₇ , Jennifer A Deal ₈ , Eleanor M Simonsick ₂ , Richard N Jones ₁

Affiliation

Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Intramural Research Program, National Institute on Aging, Baltimore, MD, USA.
Department of Economics, Brown University, Providence, RI, USA.
Department of Psychiatry and Behavioral Sciences, University of California, San Francisco School of Medicine, San Francisco, CA, USA; Department of Epidemiology and Biostatistics, University of California, San Francisco School of Medicine, San Francisco, CA, USA.
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Otolaryngology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Cochlear Center for Hearing and Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Johns Hopkins Disability Health Research Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Cochlear Center for Hearing and Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Health Policy and Management, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Otolaryngology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Cochlear Center for Hearing and Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

Objective

We explored the associations of dual sensory impairment (DSI) with long-term depressive and anxiety symptoms as well as low perceived social support (LPSS) as a modifier of these associations.

Methods

Multinomial logistic regression models were used to examine the associations of DSI and single sensory impairment (hearing [pure-tone average > 25 dB] and vision [impaired visual acuity and/or contrast sensitivity]) with long-term depressive symptom (≥8 on the 10-item Center for Epidemiologic Studies-Depression Scale) and anxiety symptom (present on the Hopkins Symptom Checklist) latent classes from group-based trajectory models (rare/never; mild/moderate increasing; chronically high) among 2102 Health, Aging and Body Composition Study participants (mean age:74.0 ± 2.8 years; 51.9 % female) over 10 years. Models were adjusted by demographic characteristics and cardiovascular risk factors, and LPSS. An additional model evaluated the two-way interaction between DSI and LPSS.

Results

DSI was associated with increased risk of being chronically depressed (Risk Ratio, RR = 1.99, 95 % Confidence Interval, CI: 1.25, 3.17), not mild/moderate increasingly depressed (RR = 1.25, 95 % CI: 0.91, 1.71). DSI had increased risk of being mild/moderate increasingly anxious (RR = 1.60, 95 % CI: 1.16, 2.19) and chronically anxious (RR = 1.86, 95 % CI: 1.05, 3.27) groups, as compared to no impairments. Hearing impairment was associated with being mild/moderate increasingly anxious (RR = 1.34, 95 % CI: 1.01, 1.79). No other associations were found for single sensory impairments. LPSS did not modify associations.

Limitations

Sensory measures were time-fixed, and LPSS, depression and anxiety measures were self-reported.

Conclusions

Future research is warranted to determine if DSI therapies may lessen long-term chronically high depressive and anxiety symptoms.

中文翻译：

美国双重感觉障碍与长期抑郁和焦虑症状的关联

客观的

我们探讨了双重感觉障碍 (DSI) 与长期抑郁和焦虑症状以及低感知社会支持 (LPSS) 作为这些关联的修饰符的关联。

方法

多项逻辑回归模型用于检查 DSI 和单一感觉障碍（听力 [纯音平均 > 25 dB] 和视力 [视力受损和/或对比敏感度]）与长期抑郁症状（≥8 2102 健康、老龄化和身体成分研究参与者（平均年龄：74.0 ± 2.8 岁；51.9 % 女性）超过 10 年。模型根据人口统计学特征和心血管危险因素以及 LPSS 进行了调整。另一个模型评估了 DSI 和 LPSS 之间的双向交互。

结果

DSI 与慢性抑郁症风险增加相关（风险比，RR = 1.99，95 % 置信区间，CI：1.25，3.17），而不是轻度/中度抑郁症（RR = 1.25，95 % CI：0.91，1.71）。与无损伤相比，DSI 增加了轻度/中度日益焦虑 (RR = 1.60, 95 % CI: 1.16, 2.19) 和慢性焦虑 (RR = 1.86, 95 % CI: 1.05, 3.27) 组的风险。听力障碍与轻度/中度越来越焦虑有关（RR = 1.34, 95 % CI: 1.01, 1.79）。没有发现与单一感觉障碍有关的其他关联。LPSS 没有修改关联。