Li et al present the results of a proximity-interaction screen in mammalian cells for the effector proteins of 25 members of the Arf family of small GTPases. This study has generated an important resource for those working in several areas of cell biology and provided an initial characterisation of two new cellular roles for some of the least well studied members of this family, the regulation of PLD1 by ARL11/14 in phagocytosis, and the regulation of PI4KB by ARL5A/5B in the Golgi.

中文翻译：

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ARF 得到 BioID 治疗：我们错过了什么？

Li等人展示了在哺乳动物细胞中对小 GTP 酶 Arf 家族 25 个成员的效应蛋白进行邻近相互作用筛选的结果。这项研究为细胞生物学多个领域的工作人员提供了重要的资源，并为该家族中一些研究最少的成员提供了两种新细胞作用的初步表征，即 ARL11/14 在吞噬作用中对 PLD1 的调节，以及高尔基体中 ARL5A/5B 对 PI4KB 的调节。