The amination of alkyl alcohols is one of the most promising paths in synthesis of aliphatic amines. Herein, cerium doped nickel-based catalysts were synthesized and tested in a gas-phase amination of n-hexanol to n-hexylamine. It was found that the activity of the Ni/γ-Al₂O₃ catalyst is significantly improved by doping an appropriate amount of cerium. The presence of cerium effectively inhibits the agglomeration of nickel particle, resulting in better Ni dispersion. As Ni particle size plays critical role on the catalytic activity, higher turnover frequency of n-hexanol amination was achieved. Cerium doping also improves the reduction ability of nickel and enhances the interactions between Ni and the catalyst support. More weak acid sites were also found in those cerium doped catalysts, which promote another key step—ammonia dissociative adsorption in this reaction system. The overall synergy of Ni nanoparticles and acid sites of this Ni-Ce/γ-Al₂O₃ catalyst boosts its superior catalytic performance in the amination of n-hexanol.

烷基醇的胺化是脂肪胺合成中最有希望的途径之一。在此，合成了铈掺杂的镍基催化剂，并在正己醇气相胺化为正己胺的过程中进行了测试。发现通过掺杂适量的铈可以显着提高Ni/ γ - Al ₂ O _{3催化剂的活性。}铈的存在有效地抑制了镍颗粒的团聚，从而产生更好的镍分散。由于 Ni 粒径对催化活性起着至关重要的作用，因此n的更高周转频率实现-己醇胺化。铈掺杂还提高了镍的还原能力，增强了镍与催化剂载体之间的相互作用。在这些掺杂铈的催化剂中还发现了更多的弱酸位点，这促进了另一个关键步骤——氨解离吸附在该反应系统中。Ni-Ce/ γ - Al ₂ O ₃催化剂的 Ni 纳米颗粒和酸性位点的整体协同作用提高了其在正己醇胺化中的优异催化性能。