Pressure-driven membranes is a widely used separation technology in a range of industries, such as water purification, bioprocessing, food processing and chemical production^1,2. Despite their numerous advantages, such as modular design and minimal footprint, inevitable membrane fouling is the key challenge in most practical applications³. Fouling limits membrane performance by reducing permeate flux or increasing pressure requirements, which results in higher energetic operation and maintenance costs^4,5,6,7. Here we report a hydraulic-pressure-responsive membrane (PiezoMem) to transform pressure pulses into electroactive responses for in situ self-cleaning. A transient hydraulic pressure fluctuation across the membrane results in generation of current pulses and rapid voltage oscillations (peak, +5.0/−3.2 V) capable of foulant degradation and repulsion without the need for supplementary chemical cleaning agents, secondary waste disposal or further external stimuli^{3,8,9,10,11,12,13}. PiezoMem showed broad-spectrum antifouling action towards a range of membrane foulants, including organic molecules, oil droplets, proteins, bacteria and inorganic colloids, through reactive oxygen species (ROS) production and dielectrophoretic repulsion.

压力驱动膜是一种广泛使用的分离技术，广泛应用于水净化、生物加工、食品加工和化学生产^1,2等行业。尽管它们有许多优点，例如模块化设计和最小的占地面积，但不可避免的膜污染是大多数实际应用中的关键挑战³。结垢通过降低渗透通量或增加压力要求来限制膜性能，从而导致更高的运行和维护成本^4,5,6,7. 在这里，我们报告了一种液压响应膜 (PiezoMem)，可将压力脉冲转化为电活性响应，从而实现原位自清洁。跨膜的瞬时液压波动导致产生电流脉冲和快速电压振荡（峰值，+5.0/-3.2 V），能够降解和排斥污垢，无需补充化学清洁剂、二次废物处理或进一步的外部刺激^{3,8,9,10,11,12,13}。PiezoMem 通过活性氧 (ROS) 的产生和介电泳排斥对一系列膜污染物质（包括有机分子、油滴、蛋白质、细菌和无机胶体）显示出广谱防污作用。