Metal-based nanoparticles (MNPs) represent an emerging class of materials that have attracted enormous attention in many fields. By comparison with other biomaterials, MNPs own unique optical properties which make them a potential alternative to conventional therapeutic agents in medical applications. Especially, owing to the easy access to the skin, the use of MNPs based on their optical properties has gained importance for the treatment of a variety of skin diseases. This review provides an insight into the different optical properties of MNPs, including photoprotection, photocatalysis, and photothermal, and highlights their implications in treating skin disorders, with a special emphasis on their use in infection control. Finally, a perspective on the safety concern of MNPs for dermatological use is discussed and analyzed. The information gathered and presented in this review will help the readers have a comprehensive understanding of utilizing the photo-triggered activity of MNPs for the treatment of skin diseases.

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中文翻译：

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金属基纳米粒子的光相关活性及其对皮肤病治疗的影响

金属基纳米粒子 (MNP) 代表了一类新兴材料，在许多领域引起了极大的关注。与其他生物材料相比，MNP 具有独特的光学特性，这使其成为医疗应用中传统治疗剂的潜在替代品。特别是，由于易于接触皮肤，基于其光学特性的 MNPs 的使用在治疗各种皮肤病方面变得越来越重要。这篇综述深入了解了 MNP 的不同光学特性，包括光保护、光催化和光热，并强调了它们在治疗皮肤病方面的意义，特别强调了它们在感染控制中的应用。最后，讨论和分析了 MNPs 在皮肤病学中的安全问题。

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