Celiac Disease (CeD) is a chronic intestinal disease which occurs in 0.7–1.4% of the global population. Since the discovery of gluten as its disease-inducing antigen, CeD patients are treated with a gluten-free diet which is effective but has limitations for certain groups of patients. Accordingly, over the past few years, there is a growing interest in alternative treatment options. This review summarizes emerging pharmacological approaches, including tolerance induction strategies, tissue transglutaminase inhibition, gluten degradation, and inhibition of interleukin (IL)-15.

中文翻译：

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乳糜泻：即将出现的新疗法

乳糜泻 (CeD) 是一种慢性肠道疾病，占全球人口的 0.7-1.4%。自从发现麸质作为其疾病诱导抗原以来，CeD 患者接受无麸质饮食治疗，这种饮食有效但对某些患者群体有局限性。因此，在过去几年中，人们对替代治疗方案的兴趣日益浓厚。这篇综述总结了新兴的药理学方法，包括耐受诱导策略、组织转谷氨酰胺酶抑制、谷蛋白降解和白细胞介素 (IL)-15 的抑制。