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The Roughton–Forster equation for pulmonary diffusion: how it happened
European Respiratory Journal ( IF 24.3 ) Pub Date : 2022-07-28 , DOI: 10.1183/13993003.00789-2022
Mike Hughes 1
Affiliation  

The transfer factor of the lung for carbon monoxide (TLCO) and spirometry are our two most valued tests in functional assessment. The understanding of the physiology underpinning TLCO (or DLCO) owes much to Robert Forster's research, including the formulation of the Roughton–Forster equation [1], the topic of this editorial. His other research involved oxygen and CO2 exchange, the role of carbonic anhydrase, and gas exchange in general. Robert (Bob) had a great sense of humour, and was delightful company (figure 1). He remained interested and engaged in the TLCO until a few months before his death in September 2021.



中文翻译:

肺扩散的 Roughton-Forster 方程:它是如何发生的

一氧化碳的肺转移因子 ( T LCO ) 和肺活量测定是我们在功能评估中最有价值的两项测试。对支持T LCO(或D LCO )的生理学的理解很大程度上归功于 Robert Forster 的研究,包括本社论主题 Roughton-Forster 方程 [1] 的公式化。他的其他研究涉及氧气和 CO 2交换、碳酸酐酶的作用以及一般的气体交换。罗伯特 (Bob) 很有幽默感,与人相处愉快(图 1)。直到 2021 年 9 月去世前几个月,他一直对T LCO感兴趣并参与其中。

更新日期:2022-07-28
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