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Dual-channel lanthanide-doped nanoprobe for reliable multi-signal ratiometric detection of H2S in whole blood
Chemical Communications ( IF 4.9 ) Pub Date : 2022-07-27 , DOI: 10.1039/d2cc03360g
Zheng Wei 1 , Tianqi Cao 1 , Luoyuan Li 2 , Xingjun Zhu 3 , Jing Zhou 1 , Yuxin Liu 1, 4
Affiliation  

Wavelength-dependent absorbance of blood has impeded the development of fluorescence biodetection in whole blood. Here, by replacing the fluorescence working signal with a temperature signal, reliable H2S detection was performed in samples of whole blood. The developed system was based on a dual-channel lanthanide-doped nanoprobe, which further allowed precise serodiagnosis of acute pancreatitis.

中文翻译:

双通道镧系元素掺杂纳米探针用于可靠的多信号比率检测全血中的 H2S

血液的波长依赖性吸光度阻碍了全血荧光生物检测的发展。在这里,通过用温度信号代替荧光工作信号,在全血样本中进行了可靠的 H 2 S 检测。开发的系统基于双通道镧系元素掺杂纳米探针,进一步实现了急性胰腺炎的精确血清诊断。
更新日期:2022-07-27
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