Placental villi play a vital role in human fetal development, acting as the bridge of material exchange between the maternal and fetal. The abnormal morphology of placental villi is closely related to placental circulation disorder and pregnancy complications. Revealing placental villi three-dimensional (3D) morphology of common obstetric complications and healthy pregnancies provides a new perspective for studying the role of the placenta and its villi in the development of pregnancy diseases. In this study, we established a noninvasive, high-resolution 3D imaging platform via optical coherence tomography to reveal placental villi 3D morphological information of diseased and normal placentae. For the first time, 3D morphologies of placental villous tree structures in common obstetric complications were quantitatively revealed and corresponding 3D information could visualize the morphological characteristics of the placental villous tree from a more intuitive perspective, providing helpful information to the study of fetal development, feto-maternal material exchange, and gestational complications treatment.

中文翻译：

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光学相干断层扫描三维形态揭示人胎盘绒毛常见产科并发症

胎盘绒毛在人类胎儿发育过程中起着至关重要的作用，是母胎间物质交换的桥梁。胎盘绒毛形态异常与胎盘循环障碍及妊娠并发症密切相关。揭示常见产科并发症和健康妊娠的胎盘绒毛三维（3D）形态，为研究胎盘及其绒毛在妊娠疾病发展中的作用提供了新的视角。在这项研究中，我们通过光学相干断层扫描建立了一个无创、高分辨率的 3D 成像平台，以揭示患病和正常胎盘的胎盘绒毛 3D 形态信息。首次，