Aim To assess the role of the corneal radius of curvature (CR) in the identification of fundus tessellation in children with low myopia. Methods In the cross-sectional study, students aged 9–12 years from 24 primary schools in Shanghai were enrolled by cluster sampling. Participants underwent measurements including cycloplegic refraction and axial length. Fundus images and choroidal thickness were obtained by swept-source optical coherence tomography. Fundus tessellation was classified into four grades according to fundus photographs. Results A total of 1127 children with low myopia (spherical equivalence (SE) >−3.00 dioptre (D) but ≤−0.50 D) were included, with a mean age of 10.29±0.60 years and a mean SE of −1.44±0.69 D. Fundus tessellation was found in 591 (52.4%) cases (grade 1: 428, 38.0%; grade 2: 128, 11.4%; grade 3: 35, 3.1%). Choroidal thickness decreased as fundus tessellation grade increased (p trend <0.001). According to regression analysis, higher fundus tessellation grade was independently associated with larger CR (OR, 7.499; 95% CI 2.279 to 24.675, p=0.001). For those with CR >7.9 mm, along with CR, degree and proportion of fundus tessellation increased sharply. Conclusion Fundus tessellation existed in more than half of children with low myopia. Preliminary fundus photography conducted in children with low myopia with large CR would be necessary and beneficial to the early management of myopic fundus changes. Trial registration number [NCT02980445][1]. No data are available. [1]: /lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT02980445&atom=%2Fbjophthalmol%2F107%2F10%2F1532.atom

中文翻译：

---

角膜曲率半径在低度近视儿童眼底镶嵌早期识别中的作用

目的 评估角膜曲率半径（CR）在识别低度近视儿童眼底镶嵌中的作用。方法采用横断面研究方法，采用整群抽样的方法，对上海市24所小学的9~12岁学生进行调查。参与者接受了包括散瞳验光和眼轴长度在内的测量。通过扫源光学相干断层扫描获得眼底图像和脉络膜厚度。眼底镶嵌根据眼底照片分为四个等级。结果 共纳入1127名低度近视儿童（球镜等效度（SE）>−3.00屈光度（D）但≤−0.50 D），平均年龄10.29±0.60岁，平均SE为-1.44±0.69 D . 眼底镶嵌有591例（52.4%）（1级：428例，38.0%；2级：128例，11.4%；3级：35例，3.1%）。脉络膜厚度随着眼底镶嵌等级的增加而减少（p趋势<0.001）。根据回归分析，较高的眼底镶嵌等级与较大的 CR 独立相关（OR，7.499；95% CI 2.279 至 24.675，p=0.001）。对于CR>7.9mm的患者，随着CR的增加，眼底镶嵌的程度和比例急剧增加。结论半数以上的低度近视儿童存在眼底镶嵌。对CR较大的低度近视儿童进行初步眼底摄影是必要的，有利于近视眼底变化的早期治疗。试用注册号[NCT02980445][1]。无可用数据。[1]: /lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT02980445&atom=%2Fbjophamol%2F107%2F10%2F1532.atom