Point-of-care technology (POCT) is an important method in clinical testing in the future, which can achieve the purpose of rapid analysis. In this work, we assembled an electrochemical POC sensor for uric acid (UA) by surface modification of a screen-printed electrode. Copper nanowires were used as electrode modifiers to achieve high-performance electrochemical oxidation of UA. This electrochemical sensor can achieve linear detection of UA in the range of 10 μM to 2 mM. The detection limit of the sensor was calculated to be 2 μM. Although the detection performance of this sensor is not competitive with high-performance electrochemical sensors, it has been able to meet the needs of POC detection. At the same time, the sensor has excellent anti-interference performance. It has also been used successfully to test urine and serum samples from healthy and gout patients.

中文翻译：

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用于尿酸测量的基于电化学的护理点测试方法

即时检测技术（POCT）是未来临床检测的重要手段，可以达到快速分析的目的。在这项工作中，我们通过丝网印刷电极的表面改性组装了一种用于尿酸 (UA) 的电化学 POC 传感器。铜纳米线用作电极改性剂，以实现 UA 的高性能电化学氧化。该电化学传感器可实现 10 μM 至 2 mM 范围内 UA 的线性 检测。传感器的检测限计算为 2  μM.虽然该传感器的检测性能与高性能电化学传感器相比不具备竞争力，但已经能够满足POC检测的需要。同时，该传感器具有优异的抗干扰性能。它还成功地用于检测健康和痛风患者的尿液和血清样本。