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Calcium phosphate conversion technique: A versatile route to develop corrosion resistant hydroxyapatite coating over Mg/Mg alloys based implants
Journal of Magnesium and Alloys ( IF 17.6 ) Pub Date : 2022-07-21 , DOI: 10.1016/j.jma.2022.06.005
G.S. Hikku , C. Arthi , R.B. Jeen Robert , K. Jeyasubramanian , R. Murugesan

Globally, vast research interest is emerging towards the development of biodegradable orthopedic implants as it overcomes the toxicity exerted by non-degradable implants when fixed in the human body for a longer period. In this context, magnesium (Mg) plays a major role in the production of biodegradable implants owing to their characteristic degradation nature under the influence of body fluids. Also, Mg is one of the essential nutrients required to perform various metabolic activities by the human cells, and therefore, the degraded Mg products will be readily absorbed by the nearby tissues. Nevertheless, the higher corrosion rate in the biological environment is the primary downside of using Mg implants that liberate H2 gas resulting in the formation of cavities. Further, in certain cases, Mg undergoes complete degradation before the healing of damaged bone tissue and cannot serve the purpose of providing mechanical support. So, many studies have been focused on the development of different strategies to improve the corrosion-resistant behavior of Mg according to the requirement. In this regard, the present review focused on the limitations of using pure Mg and Mg alloys for the fabrication of medical implants and how the calcium phosphate conversion coating alters the corrosive tendency through the formation of hydroxyapatite protective films for enhanced performance in medical implant applications.



中文翻译:

磷酸钙转化技术:在镁/镁合金基植入物上开发耐腐蚀羟基磷灰石涂层的通用途径

在全球范围内,对生物可降解骨科植入物的开发产生了广泛的研究兴趣,因为它克服了不可降解植入物在人体中长时间固定时产生的毒性。在这种情况下,镁 (Mg) 在可生物降解植入物的生产中发挥着重要作用,因为它们在体液的影响下具有特征降解性质。此外,镁是人体细胞进行各种代谢活动所需的必需营养素之一,因此,降解的镁产物很容易被附近组织吸收。然而,生物环境中较高的腐蚀速率是使用释放 H 2的 Mg 植入物的主要缺点气体导致空洞的形成。此外,在某些情况下,镁在受损骨组织愈合之前会完全降解,不能起到提供机械支撑的作用。因此,许多研究都集中在根据需要开发不同的策略来提高镁的耐腐蚀性能。在这方面,本综述着重于使用纯镁和镁合金制造医疗植入物的局限性,以及磷酸钙转化涂层如何通过形成羟基磷灰石保护膜来改变腐蚀趋势,从而提高医疗植入物应用的性能。

更新日期:2022-07-21
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