The fat-to-muscle mass ratio (FMR), which integrates the antagonistic effects of fat and muscle mass, has been proposed as a useful indicator to assess disease risk independent of overall obesity. However, little is known about the association between FMR and dementia risk. We aimed to prospectively investigate the sex-specific associations between total and regional FMR and incident dementia.

中文翻译：

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总和区域脂肪与肌肉质量比以及全因痴呆、阿尔茨海默病和血管性痴呆的风险

脂肪与肌肉质量比 (FMR) 综合了脂肪和肌肉质量的拮抗作用，已被提议作为评估独立于整体肥胖的疾病风险的有用指标。然而，对于 FMR 与痴呆风险之间的关联知之甚少。我们的目的是前瞻性地调查总体和区域 FMR 与痴呆事件之间的性别特定关联。