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Determination and enantioselective separation of zilpaterol in human urine after mimicking consumption of contaminated meat using high-performance liquid chromatography with tandem mass spectrometry techniques
Rapid Communications in Mass Spectrometry ( IF 2 ) Pub Date : 2022-07-18 , DOI: 10.1002/rcm.9357
Luisa Euler 1 , Felicitas Wagener 1 , Andreas Thomas 1 , Mario Thevis 1, 2
Affiliation  

The synthetic β-adrenoreceptor agonist zilpaterol is legitimately used as an animal feed supplement in selected countries due to its known effects on lipolysis and protein biosynthesis. These pharmacological characteristics of zilpaterol have contributed to its classification as doping agent in sport by the World Anti-Doping Agency. However, the use as a feed supplement can lead to residues of the drug in edible tissues and, possibly, also in the urine of consumers.

中文翻译:

使用高效液相色谱-串联质谱技术模拟食用受污染肉类后人尿中齐帕特罗的测定和对映选择性分离

合成的 β-肾上腺素受体激动剂齐帕特罗在某些国家被合法地用作动物饲料补充剂,因为它已知对脂肪分解和蛋白质生物合成有影响。齐帕特罗的这些药理特性有助于其被世界反兴奋剂机构归类为运动中的兴奋剂。然而,用作饲料补充剂会导致药物残留在可食用组织中,并且可能还会残留在消费者的尿液中。
更新日期:2022-07-18
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