Finding sex differences in the response of patients with melanoma to BRAF/MEK-targeted therapy, Vellano et al. show that this effect is mediated by androgen receptor expression and demonstrate that androgen receptor blockers can enhance treatment response.

中文翻译：

---

AR 阻滞剂增强黑色素瘤治疗

Vellano 等人发现黑色素瘤患者对 BRAF/MEK 靶向治疗反应的性别差异。表明这种作用是由雄激素受体表达介导的，并证明雄激素受体阻滞剂可以增强治疗反应。