Aluminium (Al) is among the most abundant metals in nature, and its presence in the environment is further increasing by anthropogenic activities. In water bodies, the Al concentrations ranged between 0.001 and 50 mg/L, raising concerns about the health of aquatic organisms. For this reason, zebrafish was chosen as the model, since it is well suited for ecotoxicological studies. Adult specimens were exposed to 11 mg/L of Al for 10, 15 and 20 days to assess both the morphology and the oxidative state of muscle tissue. Considering the involvement of ROS, the activity of the main antioxidant enzymes, metallothioneins contents, but also oxidative damage and enzymes involved in energy consumption and neuromuscular transmission were assessed. Collected data showed an increase in the thickness of the endomysium and resorbed myofibrils in the organisms exposed to Al for 10 days, and an increase of myotomes' size in the organisms exposed to Al for 15 days. Moreover, the organisms exposed for less time to Al, it was evident an activation of anaerobic metabolism and the increased activity of antioxidant enzymes such as superoxide dismutase, glutathione peroxidase and glutathione S-transferases. However, these effects stabilized with increasing exposure time. In addition, only after 20 days of treatment did the oxidative damage to the proteins and the activity of acetylcholinesterase increase while the levels of metallothioneins and the lipid peroxidation were lower for all treated animals when compared to the control group. Overall, the biochemical and histological changes induced by aluminium exposure in the muscular tissue represent a relevant contribution to understanding the environmental risk due to the diffusion of this metal within the aquatic compartment.

铝 (Al) 是自然界中含量最丰富的金属之一，其在环境中的存在因人为活动而进一步增加。在水体中，铝的浓度在 0.001 到 50 毫克/升之间，引起了人们对水生生物健康的担忧。出于这个原因，斑马鱼被选为模型，因为它非常适合生态毒理学研究。将成人标本暴露于 11 mg/L 的 Al 10、15 和 20 天，以评估肌肉组织的形态和氧化状态。考虑到 ROS 的参与，评估了主要抗氧化酶的活性、金属硫蛋白含量以及氧化损伤和参与能量消耗和神经肌肉传递的酶。收集的数据显示，暴露于铝 10 天的有机体的肌内膜和再吸收的肌原纤维厚度增加，暴露于铝 15 天的有机体肌节大小增加。此外，有机体暴露于铝的时间更短，明显激活了厌氧代谢和抗氧化酶如超氧化物歧化酶、谷胱甘肽过氧化物酶和谷胱甘肽 S-转移酶的活性增加。然而，这些影响随着曝光时间的增加而稳定下来。此外，仅在治疗 20 天后，蛋白质的氧化损伤和乙酰胆碱酯酶的活性才增加，而与对照组相比，所有治疗动物的金属硫蛋白水平和脂质过氧化水平都较低。全面的，