Human monocyte-derived dendritic cells (moDCs) isolated from blood are cultured with the Adaptable Drug Affinity Conjugate (ADAC), i.e., a bispecific CD40-targeting agonistic antibody. The picture represents activated dendritic cells with the microscope picture of ADAC-activated moDCs that cluster together in their activated state. This is reported by Sara M. Mangsbo and co-workers in article number 2200008. The photo was taken by the author Ida Lauren.

中文翻译：

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纳米粒子、纳米器件和纳米技术在皮肤黑色素瘤治疗过程中的应用（Adv. Therap. 7/2022）

从血液中分离的人单核细胞衍生的树突状细胞 (moDC) 与适应性药物亲和偶联物 (ADAC) 一起培养，即一种双特异性 CD40 靶向激动抗体。该图片表示活化的树突状细胞，其中 ADAC 活化的 moDCs 在其活化状态下聚集在一起的显微镜图片。这是由 Sara M. Mangsbo 及其同事在文章编号 2200008 中报道的。照片由作者 Ida Lauren 拍摄。