Purpose

To evaluate formulas for intraocular lens (IOL) calculation in silicone oil (SO)–filled eyes.

Design

Retrospective, consecutive case series.

Methods

We conducted our study at the Department of Ophthalmology, Goethe University, Frankfurt, Germany, and included SO-filled eyes that received SO removal combined with phacoemulsification and IOL implantation. Preoperative assessments included biometry (IOLMaster 700; Carl Zeiss Meditec). To evaluate the measurements, we compared the mean prediction error, and mean and median absolute prediction error of 8 different formulas.

Results

A total of 90 eyes matched our inclusion criteria. The median absolute error was lowest in the Barrett Universal II formula (0.43 diopters [D] ± 0.75) followed by Kane (0.44 D ± 0.75), Hill–radial basis function (0.47 D ± 0.74), Holladay II (0.47 D ± 0.77), Sanders Retzlaff Kraff/theoretical (0.51 D ± 0.74), Holladay I (0.51 D ± 0.76), and Haigis and Hoffer Q (0.52 D ± 0.74 each). Regarding eyes within ±0.5 D Barrett Universal II (57.8%, 52 eyes) performed best, again followed by Kane (56.7%, 51 eyes) and Hill–radial basis function (54.4%, 49 eyes).

Conclusion

Using modern formulas for IOL calculation in oil-filled eyes improves predictability but still not as good as in unoperated eyes. This issue is created by the change in refractive index due to the SO fill and therefore a lower precision of axial length measurement and effective lens position prediction.

中文翻译：

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人工晶状体计算在视网膜脱离后硅油去除和超声乳化的硅油填充眼中使用 8 个公式

目的

评估硅油 (SO) 填充眼中人工晶状体 (IOL) 的计算公式。

设计

回顾性连续病例系列。

方法

我们在德国法兰克福歌德大学眼科进行了我们的研究，包括接受 SO 去除联合超声乳化和 IOL 植入的 SO 填充眼。术前评估包括生物测定（IOLMaster 700；Carl Zeiss Meditec）。为了评估测量结果，我们比较了 8 种不同公式的平均预测误差以及平均和中值绝对预测误差。

结果

共有 90 只眼睛符合我们的纳入标准。Barrett Universal II 公式中的中位绝对误差最低 (0.43 屈光度 [D] ± 0.75)，其次是 Kane (0.44 D ± 0.75)、Hill-径向基函数 (0.47 D ± 0.74)、Holladay II (0.47 D ± 0.77) )、Sanders Retzlaff Kraff/理论 (0.51 D ± 0.74)、Holladay I (0.51 D ± 0.76)、Haigis 和 Hoffer Q（各 0.52 D ± 0.74）。对于±0.5 D Barrett Universal II（57.8%，52 只眼）内的眼睛表现最好，其次是 Kane（56.7%，51 只眼）和 Hill-radial 基函数（54.4%，49 只眼）。

结论

在充满油的眼睛中使用现代公式计算 IOL 可提高可预测性，但仍不如未手术的眼睛。这个问题是由 SO 填充引起的折射率变化造成的，因此轴向长度测量和有效透镜位置预测的精度较低。