An Evidence-Based Guideline Improves Outcomes for Patients With Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome.,The Journal of Rheumatology

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An Evidence-Based Guideline Improves Outcomes for Patients With Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome.
The Journal of Rheumatology ( IF 3.9 ) Pub Date : 2022-07-15 , DOI: 10.3899/jrheum.211219
Maria L Taylor ₁ , Kacie J Hoyt ₂ , Joseph Han ₃ , Leslie Benson ₄ , Siobhan Case ₅ , Mia T Chandler ₁ , Margaret H Chang ₅ , Craig Platt ₁ , Ezra M Cohen ₁ , Megan Day-Lewis ₁ , Fatma Dedeoglu ₁ , Mark Gorman ₄ , Jonathan S Hausmann ₆ , Erin Janssen ₁ , Pui Y Lee ₁ , Jeffrey Lo ₁ , Gregory P Priebe ₇ , Mindy S Lo ₁ , Esra Meidan ₁ , Peter A Nigrovic ₅ , Jordan E Roberts ₁ , Mary Beth F Son ₁ , Robert P Sundel ₁ , Maria Alfieri ₈ , Jenny Chan Yeun ₈ , Damilola M Shobiye ₈ , Barbara Degar ₉ , Joyce C Chang ₁ , Olha Halyabar ₁ , Melissa M Hazen ₁ , Lauren A Henderson ₁₀

Affiliation

M.L. Taylor, BS, M.T. Chandler, MD, C. Platt, MD, PhD, E.M. Cohen, MD, M. Day-Lewis, RN, MSN, CPNP, F. Dedeoglu, MD, E. Janssen, MD, PhD, P.Y. Lee, MD, PhD, J. Lo, MD, M.S. Lo, MD, PhD, E. Meidan, MD, J.E. Roberts, MD, M.B.F. Son, MD, R.P. Sundel, MD, J.C. Chang, MD, MSCE, O. Halyabar, MD, M.M. Hazen, MD, L.A. Henderson, MD, MMSc, Division of Immunology, Boston Children's Hospital, Boston, Massachusetts.
K.J. Hoyt, MSc, Division of Immunology, Boston Children's Hospital, Boston, Massachusetts, and Virginia Tech Carilion School of Medicine, Roanoke, Virginia.
J. Han, BS, Icahn School of Medicine at Mount Sinai, New York, New York.
L. Benson, MD, M. Gorman, MD, Division of Neurology, Boston Children's Hospital, Boston, Massachusetts.
S. Case, MD, M.H. Chang, MD, PhD, P.A. Nigrovic, MD, Division of Immunology, Boston Children's Hospital, and Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, Massachusetts.
J.S. Hausmann, MD, Division of Immunology, Boston Children's Hospital, and Division of Rheumatology and Clinical Immunology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
G.P. Priebe, MD, Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, Massachusetts.
M. Alfieri, MPH, J. Chan Yeun, MSPH, D.M. Shobiye, MPH, Department of Pediatric Quality Program, Boston Children's Hospital, Boston, Massachusetts.
B. Degar, MD, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
M.L. Taylor, BS, M.T. Chandler, MD, C. Platt, MD, PhD, E.M. Cohen, MD, M. Day-Lewis, RN, MSN, CPNP, F. Dedeoglu, MD, E. Janssen, MD, PhD, P.Y. Lee, MD, PhD, J. Lo, MD, M.S. Lo, MD, PhD, E. Meidan, MD, J.E. Roberts, MD, M.B.F. Son, MD, R.P. Sundel, MD, J.C. Chang, MD, MSCE, O. Halyabar, MD, M.M. Hazen, MD, L.A. Henderson, MD, MMSc, Division of Immunology, Boston Children's Hospital, Boston, Massachusetts;

To compare clinical outcomes in children with hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) who were managed before and after implementation of an evidence-based guideline (EBG).

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